Skip to main content

Table 4 Prognostic features (PFS) in young patients (≤50 years), Cox regression analyses

From: Are there candidates for high-dose chemotherapy in ovarian carcinoma?

 

Univariate analysis

Multivariate analysis

 

N

HR

95CI

p-value

N

HR

95CI

p-value

OMS (0-1 vs 2-3)

36

1.76

0.71-4.38

0.22

    

FIGO (IIIc vs IV)

52

0.57

0.25-1.33

0.19

    

Histology (serous vs others)

52

0.81

0.51-1.56

0.52

    

Grade (1-2 vs 3)

31

1.31

0.83-2.08

0.25

    

Serous grade 3 (vs others)

31

1.06

0.59-1.88

0.85

    

Surgery (complete vs non complete)

52

0.29

0.15-.058

4.97 E-07

51

0.43

0.19-0.94

0.034

Complete clinical remission (Yes vs No)

51

0.22

0.11-0.45

3.65 E-05

51

0.33

0.15-0.74

0.007

CA-125 (normal vs >normal)

44

1.87

0.84-4.16

0.12

    

Treatment (CCA vs HDC)

52

2.44

1.14-5.25

0.02

51

2.31

1.06-5.04

0.036

  1. PFS, progression-free survival; N, number of cases with data available; 95CI, 95% confidence interval; HR, hazard ratio; OMS, performance status; CCA, conventional chemotherapy alone; HDC, high-dose chemotherapy.