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Table 1 Distributions of select variables (covariate data) in the cases and controls and test of the Hardy-Weinberg equilibrium for the SNPs

From: Polymorphisms in the p63 and p73 genes are associated with ovarian cancer risk and clinicopathological variables

Variables Cases, n = 308 Controls, n = 324 P
Age, year (mean ± SD) 52.90 ± 13.26 49.89 ± 13.48 0.082
Body mass index, kg/m2   0.23
< 23 85 (27.6) 92 (28.4)
23-29 157 (51.0)) 178 (54.9))
≥ 29 66 (21.4) 54 (16.7)
Number liveborn, n (%)   0.064
0 19 (6.2) 17 (5.2)
1-2 227 (73.7) 258 (79.6)
≥ 3 62 (20.1) 49 (15.1)
Oral contraceptive use, n (%)   0.49
never 184 (59.7) 201 (62.0)
1-48 months 55 (17.9) 47 (14.5)
≥ 48 months 69 (22.4) 76 (23.5)
Cigarette smoking    0.76
Yes 6 (1.9) 4 (1.2)
No 302 (98.1) 320 (98.8)
Ovarian caner family history    0.003a
Yes 29 (9.4) 7 (2.2)
No 279 (90.6) 317 (97.8)
Hardy-Weinberg equilibrium    > 0.05b
rs 4648551 χ2 = 22.3; P =0.98 χ2 = 0.05; P =0.99  
rs 6695978 χ2 = 0.04; P =0.81 χ2 = 10.19; P =0.85  
rs 873330 χ2 = 0.16; P =0.72 χ2 = 0.10; P =0.75  
  1. a. There are no statistically significant differences between the two groups in the select variables (covariate data) except ovarian cancer family history.
  2. b. P >0.05 indicate genotype distributed frequencies in the cases and controls conformed with Hardy-Weinberg genetic equilibrium.