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Table 2 Logistic regression analyses on associations between p63 rs873330, p73 rs4648551, rs6695978 and risk of ovarian cancer

From: Polymorphisms in the p63 and p73 genes are associated with ovarian cancer risk and clinicopathological variables

Gene and SNP Genotype of SNP No. of subjects (%) Adjusteda
Controls Cases P OR (95 % CI)
p63
rs873330 T > C TT 182 (56.7) 160 (52.0) 0.142 1.00 (ref)
TC 118 (36.8) 122 (39.6)   1.15 (0.88-1.52)
CC 21 (6.5) 26 (8.4) 1.21 (0.78-1.89)
T allele 482 (75.1) 442 (71.8)  
C allele 160 (24.9) 174 (28.2) 0.098 1.16 (0.79-1.68)
p73
rs4648551 G > A GG 316 (97.5) 296 (96.1) 0.936 1.00 (ref)
GA 8 (2.5) 10 (3.3)   1.05 (0.91-1.22)
AA 0 (0.0) 2 (0.6)  
G allele 640 (98.8) 602 (97.7)  
A allele 8 (1.2) 14 (2.3) 0.558 1.41 (0.99-1.93)
rs6695978 G > A GG 240 (74.1) 198 (64.3) 0.004 1.00 (ref)
  GA 73 (22.5) 94 (30.5)   1.64 (1.37-1.95)
  AA 11 (3.4) 16 (5.2) 1.81 (1.56-2.14)
  G allele 553 (85.3) 490 (79.5)  
  A allele 95 (14.7) 126 (20.5) 0.003 1.55 (1.07-2.19)
  1. a. OR and 95% CI represent odds ratios and 95% confidence intervals from logistic regression analysis, adjusted for age, BMI, number liveborn, oral contraceptive use, cigarette smoking, ovarian cancer family history.
  2. All statistical tests were two-sided with a significance level of P ≤ 0.05.