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Table 2 Relationship between MMP-2, MMP-9 and type IV collagen expression and clinic-pathological parameters in 48 patients with tongue carcinoma

From: Changes in the expression of MMP2, MMP9, and ColIV in stromal cells in oral squamous tongue cell carcinoma: relationships and prognostic implications

Variable MMP-2 MMP-9 Type IV collagen  
Stromal cells P Tumour cells P Stromal cells P Tumour cells P Low High P
Low High Low High Low High Low High   
Gender Male 14 22 1.000 31 5 1.000 6 30 0.672 11 25 1.000 24 12 0.139
Female 5 7 11 1 3 9 4 8 11 1
Age <55 9 12 0.683 18 3 1.000 5 16 0.477 5 16 0.327 17 4 0.269
≥55 10 17 24 3 4 23 10 17 18 9
Differentiation Advanced 11 13 0.2 24 0 0.022 7 17 0.137 8 16 0.756 15 9 0.104
Medium/poor 8 16 18 6 2 22 7 17 20 4
Clinical stage I+II 12 15 0.435 21 6 0.029 8 19 0.058 9 18 0.724 18 9 0.269
III+IV 7 14 21 0 1 20 6 15 17 4
T stage T1+T2 19 26 0.267 40 5 0.336 9 36 1.000 15 30 0.542 32 13 0.553
T3+T4 0 3 2 1 0 3 0 3 3 0
Recurrence No 15 18 0.217 28 5 0.650 6 27 1.000 12 21 0.328 22 11 0.182
Yes 4 11 14 1 3 12 3 12 13 2
Lymph node involvement No 10 1 <0.001 11 0 0.313 6 5 0.002 8 3 0.002 5 6 0.048
Yes 9 28 31 6 3 34 7 30 30 7
  1. Correlation was significant at the 0.05 level (two-tailed).
  2. Correlation was significant at the 0.01 level (two-tailed).