Plasma specific miRNAs as predictive biomarkers for diagnosis and prognosis of glioma

Table 3 Candidate miRNAs for investigation in the plasma of GBM

miRNA	Previous association with Glioblastoma
miR-21	High levels of miR-21 were first reported in glioblastoma
	tumors and cell lines compared to normal
	brain tissue [11, 12].
miR-15b	Down-regulated in glioblastoma tissue compared to
	normal brain tissue [14]
miR-222/221	Increased expression in glioblastoma tissue compared to
	normal brain tissue [13]
miR-128	Down-regulated in glioblastoma tissue compared to
	normal brain tissue [13]
miR-181a/b/c	Down-regulated in glioblastoma tissue compared to
	normal brain tissue [13]
miR-342-3p	Expression level decreased in blood of the glioblastoma
	patients compared to th heathy donors [10]

ISSN: 1756-9966