Table 1 Study characteristics for the included studies
Autor (year-country) | Total number of patients | Median age (range) | Male: Female | Adequacy of antibody methods | Blinding of Cdx2 evaluation | ||
|---|---|---|---|---|---|---|---|
| Â | Cdx2 positive | Cdx2 negative | Â | Cdx2 positive | Cdx2 negative | Â | Â |
Ge [34] | 59 | 107 | 52.2 | 37:22 | 51:56 | Yes | Yes |
(2008-china) |  |  | (32–72) |  |  |  |  |
Okayama [14] | 55 | 80 | 63.4 | 46:9 | 45:35 | Yes | Yes |
(2009-Japan) |  |  | (31–87) |  |  |  |  |
Kim [5] | 150 | 109 | 57.8 | 114:36 | 61:48 | Yes | Yes |
(2006- Korea) | Â | Â | Â | Â | Â | Â | Â |
Roessler [15] | 109 | 81 | 61.1 | 57:52 | 33:48 | Yes | Yes |
(2005-Germany) | Â | Â | Â | Â | Â | Â | Â |
Fan [16] | 40 | 69 | 59 | 33:7 | 42:27 | Yes | Yes |
(2005-china) |  |  | (29–82) |  |  |  |  |
Bai [17] | 36 | 55 | 62.78 | 28:8 | 43:12 | Yes | Yes |
(2007-china) |  |  | (19–87) |  |  |  |  |
Zhang [27] | 57 | 52 | 62.43 | Unclear | Unclear | Yes | Yes |
(2009-Japan) | Â | Â | Â | Â | Â | Â | Â |
Zhou [28] | 49 | 81 | 52 | 40:9 | 49:32 | Yes | Unclear |
(2006-china) |  |  | (34–73) |  |  |  |  |
Hu [29] | 27 | 25 | 57 | Unclear | Unclear | Yes | Unclear |
(2009-china) |  |  | (35–78) |  |  |  |  |
Liu [30] | 25 | 25 | 53.2 | 20:5 | 18:7 | Yes | Yes |
(2007-China) |  |  | (38–74) |  |  |  |  |
Oz [26] | 37 | 33 | 64.62 | Unclear | Unclear | Yes | Yes |
(2011-Turkey) |  |  | (26–80) |  |  |  |  |
Qin [12] | 41 | 44 | 61.75 | 30:11 | 30:14 | Yes | Yes |
(2012-China) |  |  | (20–87) |  |  |  |  |
Chu [31] | 30 | 37 | 61 | 23:7 | 26:11 | Yes | Yes |
(2011-china) |  |  | (35–87) |  |  |  |  |