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Table 2 Summary ORs for various contrasts of XRCC3 Thr241Met gene polymorphisms in this meta-analysis

From: XRCC3 Thr241Met gene polymorphisms and lung cancer risk: a meta-analysis

Subgroup analysis exon7 genotype
Contrast studies OR(95%) Ph
Total T/T vs C/C 17 0.99(0.86-1.15) 0.315
(C/T + T/T) vs C/C 0.95(0.87-1.04) 0.228
Ethnicity    
Asian T/T vs C/C 5 0.92(0.71-1.09) 0.216
(C/T + T/T) vs C/C 0.94(0.77-1.15) 0.545
Caucasian T/T vs C/C 10 0.94(0.87-1.13) 0.090
(C/T + T/T) vs C/C 0.95(0.85-1.06) 0.056
Mixed population T/T vs C/C 2 1.04(0.77-1.43) 0.190
(C/T + T/T) vs C/C 1.00(0.73-1.37) 0.823
Histological type    
SCC T/T vs C/C 2 0.94(0.78-1.58) 0.164
(C/T + T/T) vs C/C 0.91(0.48-1.74) 0.215
AC T/T vs C/C 3 1.09(0.72-1.38) 0.535
(C/T + T/T) vs C/C 1.05(0.79-1.40) 0.331
Smoking status    
Smoker T/T vs C/C 4 0.98(0.72-1.45) 0.006
(C/T + T/T) vs C/C 0.93(0.63-1.37) 0.001
Non-smoker T/T vs C/C 4 0.99(0.78-1.51) 0.230
(C/T + T/T) vs C/C 0.92(0.62-1.37) 0.186
  1. Ph P value of Q-test for heterogeneity test.