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Table 1 Expression pattern of survivin, p53 and Bcl-2 in liver metastases pre- and post - 90 Y-RE

From: Decrease of survivin, p53 and Bcl-2 expression in chemorefractory colorectal liver metastases may be predictive of radiosensivity after radioembolization with yttrium-90 resin microspheres

Biomarkers

Number of patients (%)

 

Pre-90Y-RE (N = 29)

Post-90Y-RE (N = 15)

Survivin N (%)

  

Negative (≤ 20)

5 (16.2)

10 (66.7)

Positive (> 20)

24 (77.4)

5 (33.3)

p53 N (%)

  

Negative (≤ 10)

2 (6.9)

4 (26.7)

Positive (> 10)

27 (93.1)

11 (73.3)

Bcl-2 N (%)

  

Negative (≤ 5)

18 (62.1)

11 (73.3)

Positive (> 5)

11 (37.9)

4 (26.7)

Ki-67 N (%)

  

Negative (<50)

11 (37.5)

9 (60.0)

Positive (≥ 50)

18 (62.5)

6 (40.0)