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Table 2 Comparison of clinical variables between the overall series of patients and the series with liver biopsies pre- and post- 90 Y-RE

From: Decrease of survivin, p53 and Bcl-2 expression in chemorefractory colorectal liver metastases may be predictive of radiosensivity after radioembolization with yttrium-90 resin microspheres

Baseline Characteristics

Patients

Age (years)*

Time to RE**

FU months***

Sex N° (%)

PT site N° (%)

Met N° (%)

Liver involvement N° (%)

PS N° (%)

Pre BV N° (%)

Pre CTX N° (%)

    

M

F

Colon

Rectum

≤ 4

> 4

<25%

> 25%

0

≥ 1

No

Yes

No

Yes

Overall Series (N = 50)

64

19

14

37

13

41

9

21

29

20

7

35

15

39

11

45

5

(34–38)

(6–71)

(2–49)

(74)

(26)

(82)

(18)

(42)

(58)

(40)

(54)

(70)

(30)

(78)

(22)

(90)

(10)

Pre/Post RE series (N = 13)

58

21

15

9

4

11

2

4

9

30

6

9

4

9

4

12

1

(40–75)

(9–53)

(3–49)

(69)

(31)

(85)

(15)

(31)

(69)

(60)

(46)

(69)

(31)

(69)

(31)

(92)

(8)

P value

0.11

0.50

0.99

0.49

0.99

0.54

0.54

0.99

0.49

0.99

  1. * mean (range); ** Months from diagnosis to 90Y-RE; ***Follow up post-90Y-RE;
  2. M, male; F, female; PT, Primary Tumor; Met, Metastases; PS, Performance Status; BV, bevacizumab; CTX, cetuximab.