Figure 3

Downregulated SOX7 in NSCLC compared to matched normal lung samples . (A) Waterfall graph showing SOX7 mRNA expression in 62 paired human NSCLCs compared to normal lung tissue from the same patient. SOX7 mRNA expression was normalized to β-actin mRNA. (B) Statistical analysis of SOX7 mRNA expression in 62 paired human NSCLCs and normal lung tissues. Delta threshold cycle value (DCt) was calculated from the given threshold (Ct) value by the formula DCt = (Ct SOX7 – Ct β-actin) in each sample. P value was calculated with Paired T-test. (C) Relationship between significant SOX7 mRNA levels in the NSCLC samples and clinicopathological features of the patients and their NSCLC. Statistical differences were observed in histological differences (p=0.0222). The p values were calculated with Mann–Whitney T-test.