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Table 3 Summary of methylation analysis of SOX7

From: SOX7 is down-regulated in lung cancer

Cell Lines

SOX7 Western

BS (-687 and -493)

MSP (-683 and -493)

BS (-71 to +251)

MSP (+192 and +321)

H23

-

(98%)

M

(<1%)

U

H460

+/-

(92%)

M

(0%)

U

H820

-

(70%)

M

(<1%)

U

H1299

-

(85%)

M

(8%)

U, M

H1975

-

(99%)

M

(99%)

U, M

HCC827

-

(80%)

M

(3%)

U, M

HCC2279

-

(75%)

M

(75%)

U, M

HCC2935

-

Deleted

Deleted

Deleted

Deleted

HCC4006

-

N.D.

U, M

(0%)

N.D.

PC14

++

N.D.

M

(<%)

N.D.

  1. -, +/-, ++: no, slight, moderate SOX7 protein expression.
  2. BS, Bisulfite sequencing; MSP, Methylation specific PCR; U, Unmethylated; M, Methylated; N.D., Not done.