Figure 3
From: Suppression of STIM1 inhibits human glioblastoma cell proliferation and induces G0/G1 phase arrest
Effect of downregulation of STIM1 on cell cycle progression in U251 cells. Cell cycle distribution was performed by flow cytometric analysis. (A) Representative flow cytometric histograms at 24 hrs showing the distribution of cell cycle. (B) Representative flow cytometric histograms at 48 hrs showing the distribution of cell cycle. (C) Representative flow cytometric histograms at 72 hrs showing the distribution of cell cycle. (D) Knockdown of STIM1 by RNAi in U251 cells induced cell cycle arrest in G0/G1 phase at 24 hrs after transduction. (E) Knockdown of STIM1 by RNAi in U251 cells induced cell cycle arrest in G0/G1 phase at 48 hrs after transduction. (F) Knockdown of STIM1 by RNAi in U251 cells induced cell cycle arrest in G0/G1 phase at 72 hrs after transduction.