Table 2 Effects of HU compounds on proliferation of several cancer cell lines

I

H

H

H

>100

>100

>100

>100

>100

II

n-hexyl

H

H

23 ± 0.12

28.13 ± 0.07

41 ± 0.20

34.91 ± 3.82

>100

III

H

H

H

>100

>100

>100

>100

>100

IV

n-hexyl

H

H

45.6 ± 0.20

37.3 ± 0.34

38 ± 0.12

28.8 ± 0.04

30.7 ± 0.12

V

n-hexyl

H

H

H

7.0 ± 0.10

18.7 ± 0.06

24.3 ± 0.20

19.8 ± 0.02

12.9 ± 0.06

VI

H

n-hexyl

H

H

-

>100

>100

>100

>100

VII

H

n-hexyl

CH₃

H

-

>100

>100

>100

>100

VIII

H

H

CH₃

n-hexyl

-

>100

>100

>100

>100

IX

-CH₃

n-butyl

CH₃

H

24.5 ± 0.15

12 ± 0.03

17.9 ± 0.20

51 ± 0.02

17.6 ± 0.05

X

H

n-butyl

CH₃

H

35 ± 0.64

>100

>100

>100

>100

XI

H

n-butyl

H

H

>100

>100

>100

>100

>100

XII

-CH₃

n-hexyl

CH₃

H

10.7 ± 0.15

16.2 ± 0.03

18.8 ± 0.03

>100

21.0 ± 0.04

XIII

H

n-hexyl

CH₃

H

14.1 ± 0.15

13.9 ± 0.04

20.1 ± 0.20

>100

18.1 ± 0.04

XIV

H

n-hexyl

H

H

>100

>100

>100

>100

>100

H331

15.0 ± 0.09

24.5 ± 0.15

32.0 ± 0.15

34.6 ± 0.23

21.8 ± 0.03