Figure 1

Tau protein expression by IHC (a-d). Tau 0 (a) - completely negative staining with anti-Tau antibody in tumor cells (left). Moderately intense staining of fallopian tube epithelium on the right (double arrows) serves as internal positive control (magnification 200×). Tau 1+ (b) Adenocarcinoma cells with weak focal expression of Tau protein (magnification 200×). Tau 2+ (c) Moderately intense staining of tumor cells similar to pattern of staining of superficial ovarian epithelium (arrow) (magnification 200×). Tau 3+ (d) Intense and diffuse staining as dark cytoplasmatic granules.