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Table 4 Summary of mutational analysis in NSCLC patients with E2A-PBX1 fusion transcripts

From: Detection of E2A-PBX1 fusion transcripts in human non-small-cell lung cancer

  

Total (%)

K-P-E-

K + P-E-

K-P + E-

K + P + E-

K-P + E+

K-P-E+

K + P-E+

K + P + E+

Total

 

22 (100)

12 (54.5)

7 (31.8)

1 (4.5)

1 (4.5)

1 (4.5)

   

Gender

F

15 (100)

7 (46.7)

5 (33.3)

1 (6.7)

1 (6.7)

1 (6.7)

   
 

M

7 (100)

5 (71.4)

2 (28.6)

      

Race

Caucasian

16 (100)

8 (50.0)

5 (31.3)

1 (6.3)

1 (6.3)

1 (6.3)

   
 

Asian

3 (100)

2 (66.7)

1 (33.3)

      
 

Middle eastern

1 (100)

1 (100)

       
 

Hispanic

2 (100)

1(50.0)

1 (50.0)

      

Smoking status

NS

4 (100)

4 (100)

       
 

S

18 (100)

8 (44.4)

7 (38.9)

1 (5.6)

1 (5.6)

1 (5.6)

   

Stage

I

12 (100)

8 (66.7)

3 (25.0)

1 (8.3)

     
 

II

2 (100)

1 (50.0)

1 (50.0)

      
 

III

5 (100)

2 (40.0)

2 (40.0)

  

1 (20.0)

   
 

IV

3 (100)

1 (33.3)

1 (33.3)

 

1 (33.3)

    

Histology

AIS

16 (100)

8 (50.0)

5 (31.3)

1 (6.3)

1 (6.3)

1 (6.3)

   
 

Invasive Adc

5 (100)

3 (60.0)

2 (40.0)

      
 

LCC

1 (100)

1 (100)

       
  1. K: k-ras codon 12; P: p53 exons 4-8; E: EGFR exons 19-21.