Figure 8
From: Cinnamic acid induces apoptotic cell death and cytoskeleton disruption in human melanoma cells
Cytoskeleton organization in NGM cells treated with 3.2 mM cinnamic acid. The cells were treated with the drug for 48 hours. F-actin (green) was stained with phalloidin FITC-conjugated. Microtubules (blue) were labeled with anti-α and β tubulin and secondary antibody CY-5-conjugated. DNA was counterstained with propidium iodide (red). The images were obtained by Laser Scanning Confocal Microscopy. Note that there are cells with normal cytoskeletal organization (left column) and cells with drastic morphological changes (intermediate and right columns).