From: Cinnamic acid induces apoptotic cell death and cytoskeleton disruption in human melanoma cells
Cell line | Group | Micronucleated cells | Cells with nuclear buds | Binucleated cells | Multinucleated cells |
---|---|---|---|---|---|
HT-144 | Control | 1.97 ± 0.04 | 0.20 ± 0.05 | 1.83 ± 0.02 | 0.43 ± 0.06 |
0.05 mM | 2.01 ± 0.06 | 0.24 ± 0.06 | 1.79 ± 0.04 | 0.52 ± 0.03 | |
0.40 mM | 3.13 ± 1.03a | 0.40 ± 0.02 | 4.23 ± 1.03a | 0.67 ± 0.04 | |
3.20 mM | 6.07 ± 1.45b | 1.30 ± 0.02b | 5.87 ± 0.98a | 1.17 ± 0.12a | |
NGM | Control | 1.38 ± 0.06 | 0.15 ± 0.01 | 0.20 ± 0.03 | 0.05 ± 0.02 |
0.05 mM | 1.27 ± 0.04 | 0.19 ± 0.04 | 0.29 ± 0.02 | 0.25 ± 0.08 | |
0.40 mM | 1.15 ± 0.01 | 0.10 ± 0.03 | 0.37 ± 0.07 | 0.00 ± 0.00 | |
3.20 mM | 3.07 ± 0.03a | 0.44 ± 0.02a | 0.53 ± 0.06 | 0.00 ± 0.00 |