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Figure 5 | Journal of Experimental & Clinical Cancer Research

Figure 5

From: [18F]Fluorodeoxyglucose accumulation as a biological marker of hypoxic status but not glucose transport ability in gastric cancer

Figure 5

Correlation between mean standardized uptake value and tumor size, hypoxia-inducible factor 1α mRNA levels, or proliferating cell nuclear antigen mRNA levels in intestinal and non-intestinal gastric cancers. (a) Spearman’s correlation analysis indicated a possible correlation between standardized uptake value (SUV) and tumor size in intestinal cancers (rs= 0.50, P < 0.05). (b) No association was found between SUV and proliferating cell nuclear antigen (PCNA) mRNA expression. (c) A weak association was observed between SUV and hypoxia-inducible factor 1α (HIF1α) mRNA expression (rs = 0.48, P < 0.05). (d) In non- intestinal cancer specimens, SUV was not correlated to tumor size. (e) No association was found between SUV and PCNA expression. (f) A significant correlation between SUV and HIF1α mRNA expression was observed (rs = 0.56, P < 0.01). Data are expressed as mean ± SEM. *P < 0.05. HIF1α; Hypoxia-inducible factor 1α, PCNA; Proliferating cell nuclear antigen, SUV; Standardized Uptake Value.

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