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Table 1 Demographic, clinical and biological characteristics of all donors

From: FOXP3 gene polymorphism is associated with hepatitis B-related hepatocellular carcinoma in China

Characteristics

HCC n(%)

CHB n(%)

HEAL n(%)

P value

n = 392

n = 344

n = 372

 

Age

<55

252(64.3)

223(64.8)

245(65.9)

0.90

≥55

140(35.7)

121(35.2)

127(34.1)

 

Gender

Male

345(88.0)

267(77.6)

306(82.3)

0.001

Female

47(12.0)

77(22.4)

66(17.7)

 

Alcohol abuse

Absent

75(19.1)

44(12.8)

31(8.3)

<0.001

Present

317(80.9)

300(87.2)

341(91.7)

 

Cirrhosis

Absent

50(12.8)

331(96.2)

372

 

Present

342(87.2)

13(3.8)

0

 

Anti-HCV positive

 

0

0

0

 

HBsAg positive

 

364(92.9)

344(100.0)

0

 

AFP(ng/ml)

 

923.3 ± 597.1

7.6 ± 6.9

 

<0.001

ALT(IU/L)

 

51.0 ± 24.0

54.0 ± 41.0

21.0 ± 8.1

0.30

AST(IU/L)

 

36.3 ± 29.4

45.3 ± 34.3

26.1 ± 6.9

0.67

GGT(IU/L)

 

27.7 ± 23.5

39.4 ± 35.7

19.5 ± 17.1

0.56

TBIL(μmol/L)

 

16.4 ± 12.6

19.0 ± 7.3

12.1 ± 4.2

0.56

  1. Alanine aminotransferase (ALT), aspartate aminotransferase (AST), γ-glutamyl transpeptidase (GGT) and total bilirubin (TBIL), Alpha Fetoprotein (AFP).