From: FOXP3 gene polymorphism is associated with hepatitis B-related hepatocellular carcinoma in China
Characteristics | HCC n(%) | CHB n(%) | HEAL n(%) | P value | |
---|---|---|---|---|---|
n = 392 | n = 344 | n = 372 | |||
Age | <55 | 252(64.3) | 223(64.8) | 245(65.9) | 0.90 |
≥55 | 140(35.7) | 121(35.2) | 127(34.1) | ||
Gender | Male | 345(88.0) | 267(77.6) | 306(82.3) | 0.001 |
Female | 47(12.0) | 77(22.4) | 66(17.7) | ||
Alcohol abuse | Absent | 75(19.1) | 44(12.8) | 31(8.3) | <0.001 |
Present | 317(80.9) | 300(87.2) | 341(91.7) | ||
Cirrhosis | Absent | 50(12.8) | 331(96.2) | 372 | |
Present | 342(87.2) | 13(3.8) | 0 | ||
Anti-HCV positive | 0 | 0 | 0 | ||
HBsAg positive | 364(92.9) | 344(100.0) | 0 | ||
AFP(ng/ml) | 923.3 ± 597.1 | 7.6 ± 6.9 | <0.001 | ||
ALT(IU/L) | 51.0 ± 24.0 | 54.0 ± 41.0 | 21.0 ± 8.1 | 0.30 | |
AST(IU/L) | 36.3 ± 29.4 | 45.3 ± 34.3 | 26.1 ± 6.9 | 0.67 | |
GGT(IU/L) | 27.7 ± 23.5 | 39.4 ± 35.7 | 19.5 ± 17.1 | 0.56 | |
TBIL(μmol/L) | 16.4 ± 12.6 | 19.0 ± 7.3 | 12.1 ± 4.2 | 0.56 |