Figure 4

Let- 7b increased cisplatin induced G0/ G1 arrest. U251R cells were transfected with scramble (SCR) (A) or Let-7b mimics (B) and then treated with cisplatin; cell cycle was detected by flow cytometry. The percentage of cells in different cell cycle phases was calculated (C). Data is presented from three independent experiments, and the symbol * indicates statistical difference (p < 0.05).