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Table 2 Comparison of OPN promoter between lung cancer patients and healthy controls

From: Osteopontin genetic variants are associated with overall survival in advanced non-small-cell lung cancer patients and bone metastasis

  Controls Patients   Lung cancer
  n n P LN(+) LN(−) P BM(+) BM(−) P
−66 T/G          
TT 351 356 1.00 221 135 1.00 77 279 1.00
TG 9 4 0.262 2 2 0.637 2 2 0.211
−156          
G/G 155 137 1.00 83 54 1.00 26 96 1.00
G/GG 136 150 0.094 89 61 0.391 39 126 0.671
GG/GG 69 73 0.218 48 25 0.550 14 59 0.855
−443          
TT 153 164 1 49 115 1.00 23 141 1.00
CT 163 165 0.388 93 72 <0.001 36 129 0.084
CC 44 31 0.068 25 6 <0.001 20 11 <0.001
  1. Note: LN Lymph node metastasis, BM bone metastasis. P value was calculated by chi-square test and a Fisher’s exact test.