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Table 4 The genotype distribution of nt −443 in the OPN promoter by lung cancer TNM stage

From: Osteopontin genetic variants are associated with overall survival in advanced non-small-cell lung cancer patients and bone metastasis

 

The TNM stages of lung cancer

Genotypes

I + II

III + IV

P

I + II + III

IV

P

−443

      

TT

99

65

1.000

125

39

1.000

CT

72

93

0.003

123

42

0.798

CC

6

25

<0.001

11

20

<0.001