Table 4 Different characteristics according plasma EGFR mutational status
From: Detection of EGFR mutations in circulating free DNA by PNA-mediated PCR clamping
| Patients with plasma EGFR mutation | Patients without plasma EGFR mutation | P value | |
|---|---|---|---|
| (n = 10) | (n = 50) | ||
| Age | |||
| Median, years | 60.5 | 63.0 | 0.76 |
| Range | 51-76 | 38-84 | |
| Gender | |||
| Female | 7 (70.0%) | 32 (64.0%) | 1.00 |
| Male | 3 (30.0%) | 18 (36.0%) | |
| Smoking history | |||
| Nonsmoker | 8 (80.0%) | 35 (70.0%) | 0.67 |
| Ex-smoker | 1 (10.0%) | 10 (20.0%) | |
| Current smoker | 1 (10.0%) | 5 (10.0%) | |
| WHO Performance status | |||
| Normal activity | 4 (40.0%) | 19 (38.0%) | 0.94 |
| Restricted activity | 4 (40.0%) | 23 (46.0%) | |
| In bed < 50% of the time | 2 (20.0%) | 7 (14.0%) | |
| In bed > 50% of the time | - | 1 (2.0%) | |
| Tumor histology | |||
| ADC | 9 (90.0%) | 44 (88.0%) | 0.83 |
| SQC | - | 3 (6.0%) | |
| LCC | - | 1 (2.0%) | |
| NSCLC NOS | 1 (10.0%) | 1 (2.0%) | |
| Others | - | 1 (2.0%) | |
| Stage | |||
| IIIA | - | 3 (6.0%) | 0.64 |
| IIIB | 1 (10.0%) | 3 (6.0%) | |
| IV | 9 (90.0%) | 44 (88.0%) | |
| Central labotory | |||
| on-site | 5 (50.0%) | 16 (32.0%) | 0.30 |
| off-site | 5 (50.0%) | 34 (68.0%) |