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Figure 1 | Journal of Experimental & Clinical Cancer Research

Figure 1

From: Vascular endothelial cells facilitated HCC invasion and metastasis through the Akt and NF-κB pathways induced by paracrine cytokines

Figure 1

Subcutaneous tumorigenicity test of MHCC97H cells premixed with HUVECs and the expression of HCC invasion/metastasis-associated genes. (A) MHCC97H cells as well as a mixture of MHCC97H cells and HUVECs were subcutaneously implanted into nude mice as described in the “Material and methods” section. Representative tumors resected from nude mice appeared 10 days after implantation. (B) The expression of MMP2, MMP9, OPN, and CD44 were detected by qRT-PCR in subcutaneous tumors (*P < 0.05, **P < 0.01, ***P < 0.001 vs. MHCC97H cells alone).

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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