Figure 5

Regulation of the expression of HCC invasion/metastasis-associated genes by CCL2, IL-8, and CXCL16 in HCC cells. CCL2 (A), IL-8 (B), and CXCL16 (C) induced MMP2, MMP9, OPN, and CD44 expression in MHCC97H cells (*P < 0.05, **P < 0.01, ***P < 0.001 vs. the control).