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Figure 6 | Journal of Experimental & Clinical Cancer Research

Figure 6

From: Renal cancer-selective Englerin A induces multiple mechanisms of cell death and autophagy

Figure 6

EA inhibits activation of AKT and ERK kinsases.‚ÄČA498 cells were cultured with 100 nM EA or with 0.1% DMSO (control) for the indicated times and protein was Isolated. Western blot analysis was performed as described under Methods using antibodies against AKT, ERK, and AMPK and their phosphorylated counterparts. B-actin was probed to control for protein loading. (+) control; Jurkat cell extract.

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