Immunomodulatory effects of total intravenous and balanced inhalation anesthesia in patients with bladder cancer undergoing elective radical Cystectomy: preliminary results

Table 2 Perioperative clinical data of patients with bladder cancer who underwent radical cystectomy with TIVA-TCI or BAL anesthesia

	TIVA ( n. 14)	BAL (n. 14)	P TIVA vs. BAL
HB (g/dl)
Pre-anaesthesia	13.51 ±1.80	14.42 ± 1.33	0.14
Intraoperative	9.82 ±1.63	10.43 ± 1.82	0.47
5 days post-surgery	9.63 ±1.24	9.70 ± 1.35	0.86
HCT (%)
Pre-anaesthesia	39.53 ± 5.23	42.55 ± 4.47	0.14
Intraoperative	28.2 ±5.12	30.33 ± 5.41	0.52
5 days post-surgery	29.16 ±4.85	28.32 ± 3.80	0.65
Blood loss (ml)	1596 ± 365	1539 ± 418	0.70
Total amount of crystalloid received (ml)	3250 ± 1513	2875 ± 772	0.49
Total amount of colloid received (ml)	350 ± 250	300 ± 250	0.61
Blood transfusion (n)	1.15 ± 1.64	1.22 ± 1.71	0.96
Intraoperative autotransfusion (n)	0.47 ± 0.71	0.33 ± 0.62	0.82
Intraoperative body temperature (°C)	36.14 ± 0.22	36.24 ± 0.26	0.93
Intraoperative blood glucose (mg/dl)	120.04 ± 21.38	116.63 ± 23.61	0.72
Intraoperative MAP (mmHg)	103.66 ± 12.82	106.41 ± 12.13	0.60
Intraoperative CVP (cm H ₂ O)	10.32 ± 1.23	10.14 ± 1.33	0.75
Intraoperative SpO ₂ (%)	97.60 ± 0.92	96.61 ± 2.82	0.30
Arterial lactate level (mmol/l)
1 h post-surgery	0.82 ± 0.22	0.61 ± 0.34	0.82
6 h post-surgery	1.77 ± 0.32	1.87 ± 0.25	0.83
5 days post-surgery	1.32 ± 0.35	1.27 ± 0.22	0.91
Intraoperative BE (mmol/l)	0.32 ± 0.51	0.43 ± 0.38	0.53
Intraoperative PaO ₂ (mmHg)	222.21 ± 10.23	215.11 ± 23.11	0.73
Pain (Verbal Rating Scale)
1 h post-surgery	1.32 ± 0.62	1.22 ± 0.81	0.59
6 h post-surgery	1.14 ± 0.44	1.07 ± 0.51	0.54
5 days post-surgery	0.73 ± 0.56	0.82 ± 0.64	0.46

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