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Table 2 Cause-specific differences in telomeric gene expression between cirrhotic and non-cirrhotic liver samples

From: Cause-specific telomere factors deregulation in hepatocellular carcinoma

  Non-cirrhotic Cirrhotic p
  (n = 12) HBV (n = 8) HCV (n = 9) Alcohol (n = 10) For HBV For HCV For alcohol
Shelterin
POT1 0.0021 0.0000 0.0125 0.0090 0.0480 0.0100 0.0050
PTOP 0.0094 0.0000 0.0037 0.0055 0.0200 ns ns
RAP1 0.1570 0.0016 0.4210 0.4091 0.0070 0.0080 0.0060
TIN2 0.3510 0.0018 0.0510 0.0804 0.0010 ns <10-4
TRF1 0.5585 0.0117 0.2271 0.2488 <10-4 ns ns
TRF2 0.0016 0.0000 0.0016 0.0012 0.0050 ns ns
Non-Shelterin
HMRE11A 0.0187 0.0006 0.0627 0.0764 ns ns 0.0070
HMRE11B 0.0359 0.0008 0.0492 0.0886 0.0030 ns 0.0020
Ku70 0.0955 0.0045 0.1704 0.1825 <10-4 ns 0.0440
Ku80 0.0408 0.0033 0.1209 0.1316 0.0200 0.0290 0.0120
NBS1 0.0266 0.0002 0.0304 0.0403 0.0030 ns ns
RAD50 0.0030 0.0002 0.0091 0.0108 ns 0.0180 0.0500
TANK1 0.0468 0.0005 0.0788 0.0945 <10-4 ns 0.0030
TANK2 0.0129 0.0000 0.0188 0.0127 0.0200 ns ns
Pinx1 0.0131 0.0001 0.0083 0.0219 0.0020 ns 0.0210