Journal of Experimental & Clinical Cancer Research

Table 2 Cause-specific differences in telomeric gene expression between cirrhotic and non-cirrhotic liver samples

From: Cause-specific telomere factors deregulation in hepatocellular carcinoma

	Non-cirrhotic	Cirrhotic			p
	(n = 12)	HBV (n = 8)	HCV (n = 9)	Alcohol (n = 10)	For HBV	For HCV	For alcohol
Shelterin
POT1	0.0021	0.0000	0.0125	0.0090	0.0480	0.0100	0.0050
PTOP	0.0094	0.0000	0.0037	0.0055	0.0200	ns	ns
RAP1	0.1570	0.0016	0.4210	0.4091	0.0070	0.0080	0.0060
TIN2	0.3510	0.0018	0.0510	0.0804	0.0010	ns	<10-4
TRF1	0.5585	0.0117	0.2271	0.2488	<10-4	ns	ns
TRF2	0.0016	0.0000	0.0016	0.0012	0.0050	ns	ns
Non-Shelterin
HMRE11A	0.0187	0.0006	0.0627	0.0764	ns	ns	0.0070
HMRE11B	0.0359	0.0008	0.0492	0.0886	0.0030	ns	0.0020
Ku70	0.0955	0.0045	0.1704	0.1825	<10-4	ns	0.0440
Ku80	0.0408	0.0033	0.1209	0.1316	0.0200	0.0290	0.0120
NBS1	0.0266	0.0002	0.0304	0.0403	0.0030	ns	ns
RAD50	0.0030	0.0002	0.0091	0.0108	ns	0.0180	0.0500
TANK1	0.0468	0.0005	0.0788	0.0945	<10-4	ns	0.0030
TANK2	0.0129	0.0000	0.0188	0.0127	0.0200	ns	ns
Pinx1	0.0131	0.0001	0.0083	0.0219	0.0020	ns	0.0210

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ISSN: 1756-9966

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