Table 1 Relationship of L1CAM expression with pathological parameters of tumor
Clinical parameters | L1CAM | |||
|---|---|---|---|---|
Low | High | t/χ2/r | P | |
Age(yrs) | 57.86 ± 11.88 | 61.20 ± 11.85 | 3.065 | 0.002 |
Gender | 3.386 | 0.066 | ||
Male | 321 (75.0%) | 107 (25.0%) | ||
Female | 117 (67.6%) | 56 (32.4%) | ||
Location | 13.39 | 0.001 | ||
Proximal | 54 (64.3%) | 30 (35.7%) | ||
Middle | 150 (67.3%) | 73 (32.7%) | ||
Distal | 234 (79.6%) | 60 (20.4%) | ||
Size | 26.99 | 0.0001 | ||
<5 cm | 283 (80.9%) | 67 (19.1%) | ||
≥5 cm | 155 (61.8%) | 96 (38.2%) | ||
Lauren classification | 94.92 | 0.0001 | ||
Intestinal | 271 (90.6%) | 28 (9.4%) | ||
Diffuse | 167 (55.3%) | 135 (44.7%) | ||
Histology | 5.623 | 0.131 | ||
Papillary adenocarcinoma | 26 (89.7%) | 3 (10.3%) | ||
Tubular adenocarcinoma | 317 (72.2%) | 122 (27.8%) | ||
Mucinous adenocarcinoma | 29 (78.4%) | 8 (21.6%) | ||
Signet-ring cell carcinoma | 66 (68.8%) | 30 (31.2%) | ||
Histologic differentiation | 7.67 | 0.053 | ||
Well | 17 (100%) | 0 (0.0%) | ||
Moderately | 129 (73.7%) | 46 (26.3%) | ||
Poorly | 290 (71.3%) | 117 (28.7%) | ||
Others | 2 (100.0%) | 0 (0.0%) | ||
Invasion depth | 46.55 | 0.0001 | ||
T1 | 72 (90.0%) | 8 (10.0%) | ||
T2 | 123 (87.2%) | 18 (12.8%) | ||
T3 | 222 (65.7%) | 116 (34.3%) | ||
T4 | 21 (50.0%) | 21 (50.0%) | ||
TNM stages | 85.48 | 0.0001 | ||
I | 119 (93.7%) | 8 (6.3%) | ||
II | 121 (89.6%) | 14 (10.4%) | ||
III | 141 (61.0%) | 90 (39.0%) | ||
IV | 57 (52.8%) | 51 (47.2%) | ||
Lymphatic metastasis | 43.59 | 0.0001 | ||
No | 195 (88.6%) | 25 (11.4%) | ||
Yes | 243 (63.8%) | 138 (36.2%) | ||
Regional lymph nodes | 59.62 | 0.0001 | ||
PN0 | 195 (88.6%) | 25 (11.4%) | ||
PN1 | 142 (71.7%) | 56 (28.3%) | ||
PN2 | 79 (58.5%) | 56 (41.5%) | ||
PN3 | 22 (45.8%) | 26 (54.2%) | ||
Distant metastasis | 15.376 | 0.0001 | ||
No | 387 (75.9%) | 123 (24.1%) | ||
Yes | 51 (56.0%) | 40 (44.0%) | ||