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Table 2 Relationship of EPCAM expression with pathological parameters of tumor

From: L1 and epithelial cell adhesion molecules associated with gastric cancer progression and prognosis in examination of specimens from 601 patients

Clinical parameters

EPCAM

 

Low

High

t/χ2/r

P

Age(yrs)

56.85 ± 11.4

61.51 ± 12.22

4.787

0.0001

Gender

  

0.805

0.370

Male

257 (60.0%)

171 (40.0%)

  

Female

97 (56.1%)

76 (43.9%)

  

Location

  

10.37

0.006

Proximal

37 (44.0%)

47 (56.0%)

  

Middle

130 (58.3%)

93 (41.7%)

  

Distal

187 (63.6%)

107 (36.4%)

  

Size

  

40.47

0.0001

<5 cm

244 (69.7%)

106 (30.3%)

  

≥5 cm

110 (43.8%)

141 (56.2%)

  

Lauren classification

  

198.1

0.0001

Intestinal

261 (87.3%)

38 (12.7%)

  

Diffuse

93 (30.8%)

209 (69.2%)

  

Histology

  

3.136

0.371

Papillary adenocarcinoma

20 (69.0%)

9 (31.0%)

  

Tubular adenocarcinoma

254 (57.9%)

185 (42.1%)

  

Mucinous adenocarcinoma

19 (51.4%)

18 (48.6%)

  

Signet-ring cell carcinoma

61 (63.5%)

35 (36.5%)

  

Histologic differentiation

  

6.323

0.097

Well

12 (70.6%)

5 (29.4%)

  

Moderately

113 (64.6%)

62 (35.4%)

  

Poorly

227 (55.8%)

180 (44.2%)

  

Others

2 (100.0%)

0 (0.0%)

  

Invasion depth

  

107.1

0.0001

T1

73 (91.2%)

7 (8.8%)

  

T2

113 (80.1%)

28 (19.9%)

  

T3

160 (47.3%)

178 (52.7%)

  

T4

8 (19.0%)

34 (81.0%)

  

TNM stages

  

201.6

0.0001

I

119 (93.7%)

8 (6.3%)

  

II

116 (85.9%)

19 (14.1%)

  

III

99 (42.9%)

132 (57.1%)

  

IV

20 (18.5%)

88 (81.5%)

  

Lymphatic metastasis

  

119.1

0.0001

No

193 (87.7%)

27 (12.3%)

  

Yes

161 (42.3%)

220 (57.5%)

  

Regional lymph nodes

  

182.6

0.0001

PN0

193 (87.7%)

27 (12.3%)

  

PN1

118 (59.6%)

80 (40.4%)

  

PN2

42 (31.1%)

93 (68.9%)

  

PN3

1 (2.1%)

47 (97.9%)

  

Distant metastasis

  

53.42

0.0001

No

332 (65.1%)

178 (34.9%)

  

Yes

22 (24.2%)

69 (75.8%)