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Figure 8 | Journal of Experimental & Clinical Cancer Research

Figure 8

From: On and off-target effects of telomere uncapping G-quadruplex selective ligands based on pentacyclic acridinium salts

Figure 8

Expression of TRF1, TRF2 and POT1 at the telomere level: ChIP experiments on BJ-EHLT fibroblasts incubated with 0.5 μM of 1, 2 or 3 for 24 hrs. Precipitations were performed with antibodies against TRF1, TRF2 and POT1. The total DNA (input) represents 10% of genomic DNA. a: A representative ChIp experiment is shown. b: The histogram shows the densitometric evaluation of three independent experiments, with error bars indicating ± SD.

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