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Table 8 Relative expression of miRNAs in PDAC compared with matched normal pancreatic tissue controls determined by qRT-PCR

From: Candidate microRNA biomarkers of pancreatic ductal adenocarcinoma: meta-analysis, experimental validation and clinical significance

miRNA name     
Up-regulated PDAC N p- value Fold-change
miR-155 5.56±1.00 2.71±0.66 <0.001 2.11±0.41
miR-100 7.40±2.21 3.91±1.32 <0.001 2.00±0.51
miR-21 3.80±0.99 1.7±0.35 <0.001 2.25±0.44
miR-221 8.03±2.77 3.26±0.67 <0.001 2.53±0.84
miR-31 6.52±0.98 2.93±0.39 <0.001 2.12±0.47
miR-143 7.45±1.22 2.21±1.43 <0.001 2.94±0.74
miR-23a 7.80±1.18 3.44±0.73 <0.001 2.35±0.52
Down-regulated     
miR-217 2.88±1.15 10.35±3.68 <0.001 3.91±1.36
miR-148a 3.85±1.48 10.39±2.97 <0.001 2.86±0.77
miR-375 4.00±1.55 7.05±1.99 <0.001 1.76±0.36
  1. Data are expressed as the mean ± SD. N: matched normal pancreatic tissue.