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Table 8 Relative expression of miRNAs in PDAC compared with matched normal pancreatic tissue controls determined by qRT-PCR

From: Candidate microRNA biomarkers of pancreatic ductal adenocarcinoma: meta-analysis, experimental validation and clinical significance

miRNA name

    

Up-regulated

PDAC

N

p- value

Fold-change

miR-155

5.56±1.00

2.71±0.66

<0.001

2.11±0.41

miR-100

7.40±2.21

3.91±1.32

<0.001

2.00±0.51

miR-21

3.80±0.99

1.7±0.35

<0.001

2.25±0.44

miR-221

8.03±2.77

3.26±0.67

<0.001

2.53±0.84

miR-31

6.52±0.98

2.93±0.39

<0.001

2.12±0.47

miR-143

7.45±1.22

2.21±1.43

<0.001

2.94±0.74

miR-23a

7.80±1.18

3.44±0.73

<0.001

2.35±0.52

Down-regulated

    

miR-217

2.88±1.15

10.35±3.68

<0.001

3.91±1.36

miR-148a

3.85±1.48

10.39±2.97

<0.001

2.86±0.77

miR-375

4.00±1.55

7.05±1.99

<0.001

1.76±0.36

  1. Data are expressed as the mean ± SD. N: matched normal pancreatic tissue.