Table 1 Patient characteristics at baseline
Characteristic | |
|---|---|
Patients, N | 74 |
Gender, n (%) | |
Male | 46 (62.2) |
Female | 28 (37.8) |
Age, years, median (range) | 56 (23–79) |
Time from diagnosis, months, median (range) | 31 (5–206) |
Melanoma diagnosis, n (%) | |
Cutaneous | 57 (77.0) |
Uveal | 9 (12.2) |
Mucosal | 2 (2.7) |
Unknown | 6 (8.1) |
Presence of brain metastases | 11 (14.9) |
M stage, n (%) | |
M0 (unresectable stage III) | 2 (2.7) |
M1a | 16 (21.6) |
M1b | 2 (2.7) |
M1c | 53 (71.6) |
Unknown | 1 (1.4) |
ECOG PS | |
0 | 43 (58.1) |
1 | 29 (39.2) |
2 | 2 (2.7) |
LDH | |
Median (range), units/L | 466 (139–4416) |
>Upper limit of normal (480 units/L), n (%) | 37 (50) |
Number of prior therapies for metastatic disease, median (range) | 2 (1–5) |