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Table 1 Relationship between expression of Notch-1 and clinicopathologic characteristics of LAD patients

From: Expression of Notch-1 and its clinical significance in different histological subtypes of human lung adenocarcinoma

Characteristics

  

Notch-1

  
  

n

(+)

(-)

x2

P

Gender

    

0.123

0.726

 

Male

64

22

42

  
 

Female

37

14

23

  

Age (year)

    

0.240

0.624

 

≥

51

17

34

  
 

<

50

19

31

  

Histology

    

9.721

0.021*

 

APA

44

17

27

  
 

PPA

20

9

11

  
 

SPA

25

3

22

  
 

Others

12

7

5

  

Clinical stage

    

14.028

0.001**

 

I

45

25

20

  
 

II/III/V

56

11

45

  

Differentiation

    

3.850

0.05*

 

Poor

44

11

33

  
 

moderate

47

21

26

  
 

well

10

4

6

  

Lymph node Metastasis

    

4.963

0.026*

 

N0

44

21

23

  
 

N1-3

57

15

42

  

Recurrence

    

8.241

0.004**

 

present

39

10

29

  
 

absent

44

25

19

  

Smoking history

    

3.261

0.071

 

Non-smoker

64

27

37

  
 

smoker

37

9

28

  

Tumor location

    

0.08

0.777

 

Right

58

20

38

  
 

Left

43

16

27

  

Survival analysis

    

3.946

0.047*

 

Death

45

14

31

  
 

Live

38

20

18

  
 

Disconnect

18

2

16

  
  1. Abbreviation: APA acinar predominant adenocarcinoma, PPA papillary predominant adenocarcinoma, SPA solid predominant adenocarcinoma, (+) positive; (-) negative. *P < 0.05, **P < 0.01.
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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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