Figure 3From: Aberrant DNA methyltransferase expression in pancreatic ductal adenocarcinoma development and progressionKnockdown of DNMT1 and DNMT3b expression in PDAC cells. DNMT1 siRNA, DNMT3b siRNA, or their combination was transiently transfected into PDAC cell lines and then subjected to qRT-PCR (A,B) and western blotting (C) analysis for DNMT1 and DNMT3b expression. a, p < 0.05 compared with the untreated cells. b, p < 0.05 compared with the negative siRNA cells. The data are shown as the mean ± SD of six independent experiments.Back to article page