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Table 2 Summary of gene function and chromosomal localization

From: DNA Methylation profiles as predictors of recurrence in non muscle invasive bladder cancer: an MS-MLPA approach

Gene Function Chromosomal localization
TIMP metallopeptidase inhibitor 3 (TIMP3) Invasion and metastasis 22q12.3
Adenomatous polyposis coli (APC) WNT antagonist 5q22
cyclin-dependent kinase inhibitor 2A (CDKN2A) Cell-cycle control gene 9p21
MutL homolog 1, colon cancer, nonpolyposis type 2 (MLH1) DNA mismatch repair 3p22.1
Ataxia telangiectasia mutated (ATM) Cell-cycle control gene 11q23
Retinoic acid receptor, beta (RARB) Cell differentiation and proliferation 3p24.2
Hypermethylated in Cancer 1(HIC1) Putative tumor suppressor gene 17p13.3
Checkpoint with forkhead and ring finger domains (CHFR) Putative tumor suppressor gene 12q24.33
breast cancer 1, early onset (BRCA1) Maintenant of genomic stability 17q21.31
Caspase 8, apoptosis-related cysteine peptidase (CASP8) Apoptosis related gene 2q33.2
Cyclin-dependent kinase inhibitor 1B (CDKN1B) Cell-cycle control gene 12p13.2
Phosphatase and tensin homolog (PTEN) Cell-cycle regulation gene 10q23.3
Breast cancer 2, early onset (BRCA2) Maintenance of genomic stability 13q12.3
CD44 molecule (Indian blood group) (CD44) Cell-cell interaction mediator 11p12
Ras association (RalGDS/AF-6) domain family member 1 (RASSF1) Putative tumor suppressor gene 3p21.3
Death-associated protein kinase1 (DAPK) Apoptosis-related gene 9q34.1
Von Hippel-Lindau tumor suppressor (VHL) Putative tumor suppressor gene 3p25
Estrogen receptor 1 (ESR1) Cell differentiation and proliferation 6q25.1
Tumor protein p73 (TP73) Apoptotic response to DNA damage 1p36.32
Fragile histidine triad gene (FHIT) Putative tumor suppressor gene 3p14.2
Cell adhesion molecule 1 (IGSF4 (CADM1)) Cell adhesion related gene 11q23
Cadherin 13, H-cadherin (heart) (CDH13) Cell invasion 16q23.3
Glutathione S-transferase pi 1 (GSTP1) DNA damage repair gene 11q13