Table 1 Correlation between NQO1 protein expression and the clinicopathological parameters of breast cancer
From: Clinical implications of high NQO1 expression in breast cancers
Variables | No. of cases | NQO1 strongly positive cases (%) | χ 2 | Pvalue |
|---|---|---|---|---|
Age | 0.751 | 0.386 | ||
≥50 | 94 | 61 (64.9%) | ||
<50 | 82 | 48 (58.5%) | ||
Menopausal status | 1.159 | 0.282 | ||
premenopausal | 72 | 48 (66.7%) | ||
Postmenopausal | 104 | 61 (58.7%) | ||
Tumor size | 3.033 | 0.082 | ||
T1 | 97 | 51 (52.6%) | ||
T2 | 89 | 58 (65.2%) | ||
Histological grade | 11.298 | 0.004** | ||
Grade-1 | 82 | 40 (48.8%) | ||
Grade-2 | 51 | 37 (72.5%) | ||
Grade-3 | 43 | 32 (74.4%) | ||
Clinical stage | 7.050 | 0.008** | ||
0-II | 104 | 56 (53.8%) | ||
III-IV | 72 | 53 (73.6%) | ||
LN metastasis | 7.710 | 0.005** | ||
Absent | 74 | 37 (50.0%) | ||
Presence | 102 | 72 (70.6%) | ||
ER | 0.614 | 0.423 | ||
Positive | 101 | 60 (59.4%) | ||
Negative | 75 | 49 (65.3%) | ||
PR | 1.426 | 0.232 | ||
Positive | 103 | 60 (58.3%) | ||
Negative | 73 | 49 (67.1%) | ||
Her2 status | 5.534 | 0.019* | ||
Positive | 96 | 67 (69.8%) | ||
Negative | 80 | 42 (52.5%) |