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Table 2 Association between miR-34a promoter methylation and clinicopathologic features in ESCC patients

From: Inactivation of miR-34a by aberrant CpG methylation in Kazakh patients with esophageal carcinoma

CpG unit CpG site Clinical characteristic (Z/P)
Gender Age Tumor location Differentiation# Lymphatic metastasis TNM stage
Unit1 CpG_1.2 −1.396 0.163 −0.364 0.716 −1.227 0.220 0.334 0.846 −0.628 0.530 −0.838 0.402
Unit2 CpG_3 −1.075 0.282 −0.259 0.796 −1.592 0.057 5.813 0.055 −0.397 0.691 −1.440 0.150
Unit3 CpG_4 −1.558 0.119 −0.457 0.648 −1.359 0.174 2.136 0.344 −0.708 0.479 −1.019 0.308
Unit4 CpG_5 −0.039 0.969 −0.528 0.598 −0.607 0.544 1.901 0.386 −2.223 0.026* −0.625 0.532
Unit5 CpG_6 −0.168 0.866 −0.330 0.741 −1.057 0.291 2.992 0.224 −1.551 0.121 −0.732 0.464
Unit7 CpG_8.9 −0.450 0.653 −0.076 0.939 −0.093 0.926 2.221 0.896 −2.299 0.022* −2.188 0.029*
Unit9 CpG_14.15.16 −1.429 0.153 −0.360 0.719 −0.891 0.373 1.940 0.379 −0.029 0.976 −0.092 0.926
Unit10 CpG_17.18 −0.086 0.931 −0.770 0.441 −0.160 0.873 2.183 0.336 −0.612 0.541 −4.70 0.638
Unit11 CpG_19 −0.211 0.833 −0.459 0.646 −0.397 0.691 0.225 0.893 −0.328 0.743 −0.967 0.334
Unit12 CpG_20 −0.382 0.702 −0.692 0.489 −0.559 0.576 0.137 0.934 −0.328 0.743 −1.077 0.282
Unit15 CpG_23 −0.128 0.898 −0.460 0.646 −1.696 0.090 0.735 0.692 −0.711 0.477 −0.174 0.862
  1. Note: Mann–Whitney U test (two-sided); #Kruskal-Wallis H test (two-sided); *P < 0.05, bold face representing significant data.