Figure 5

Effects of ETK on cell proliferation, apoptosis, migration and invasion of RCC cells 786-O and 769-P. Comparing ETK siRNA group with negative control siRNA group, (A) Cell proliferation was significantly inhibited after ETK siRNA transfection at 48 h. (B) Flow cytometry indicated that cell apoptosis increased after ETK siRNA transfection at 48 h. (C) Cell migration was significantly inhibited after ETK siRNA transfection at 36 h. (D) Transwell matrigel invasion assay showed a significant decrease of invaded cells after ETK siRNA transfection at 48 h. (**, P<0.01).