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Table 1 Prevalence of TERT promoter hotspot mutations in soft tissue tumors

From: TERT promoter hotspot mutations are recurrent in myxoid liposarcomas but rare in other soft tissue sarcoma entities

Diagnosis

Mut (n)

Total (n)

Mut (%)

C228T (n)

C250T (n)

Myxoid liposarcoma

29

39

74%

28

1

Dedifferentiated liposarcoma

0

61

   

Pleomorphic liposarcoma

0

15

   

Leiomyosarcoma

0

27

   

Synovial sarcoma

1

25

4%

 

1

Malignant peripheral nerve sheath tumor

2

35

6%

1

1

Undifferentiated pleomorphic sarcoma

0

40

   

Myxofibrosarcoma

0

17

   

Low grade fibromyxoid sarcoma

0

9

   

Dermatofibrosarcoma protuberans

0

10

   

Solitary fibrous tumor

4

31

13%

4

 

Extraskeletal myxoid chondrosarcoma

0

8

   

Angiosarcoma

0

9

   

Alveolar soft part tumor

0

6

   

Clear cell sarcoma

0

5

   

Epithelioid sarcoma

0

4

   
 

36

341

 

33

3

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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