Shh/Gli signaling promotes cell migration in lung SCC. (A) Wound healing assays of lung SCC H2170 cells (left) and H1703 (right) treated with Gli-I, vismodegib, and recombinant Shh proteins. Representative pictures shown at 0 hr and 30 hr were taken under a light microscope (×100). (B) Quantification of the wound healing assays. The migration distance of cells was set as 100%. A p value <0.05 < 0.01 or <0.001 was indicated as *, ** or *** respectively.