Aquaporin 3 promotes epithelial-mesenchymal transition in gastric cancer

Table 1 Correlation between AQP3, E-cadherin,vimentin expression and clinicopathological features in GC

Clinicopathological features	n	AQP3			E-cadherin			Vimentin
Clinicopathological features	n	+	-	P-value	+	-	P-value	+	-	P-value
Age(yr)				0.628			0.825			0.763
≤50	32	22	10		12	20		4	28
>50	57	43	14		23	34		10	47
Gender				0.318			0.653			0.363
Male	58	40	18		24	34		11	47
Female	31	25	6		11	20		3	28
Lauren classification				0.008			0.659			0.015
Intestinal	54	34	20		20	34		4	50
Diffuse	35	31	4		15	20		10	25
Tumor size				0.303			0.816			0.758
<3.0 cm	28	18	10		10	18		5	23
≥3.0 cm	61	47	14		25	36		9	52
Tumor location				0.515			0.920			0.880
Upper third	15	10	5		6	9		3	12
Middle third	26	19	7		11	15		4	22
Lower third	48	37	9		18	30		5	41
Depth of tumor invasion				0.511			0.031			0.139
Localized in subserosa	38	13	25		20	18		3	35
Beyond subserosa	51	22	29		15	36		11	40
Lymph node metastasis							0.010			0.201
N0	12	4	8	0.002	9	3		0	12
N1–N3	77	61	16	0.002	26	51		14	63
Lymphovascular invasion				0.044			0.000			0.004
Absence	58	38	20		32	26		4	54
Presence	31	27	4		4	28		10	21

ISSN: 1756-9966