Figure 1From: Identification of novel hypermethylated genes and demethylating effect of vincristine in colorectal cancerHypermethylation of promoter CpG sites for 21 genes by methylation chip array. The methylation statuses of CpG sites in promoter CpG islands for 21 genes were identified using methylation chip array in 10 normal colon tissues, 21 CRC tissues, and 21 adjacent normal tissues. All genes were significantly strongly hypermethylated in their promoter CpG islands in CRC tissues compared with adjacent normal tissues and normal tissues (P < 0.05). N: normal colon tissues, T: CRC tissues, AN: adjacent normal tissues.Back to article page