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Table 3 Univariate analysis of clinicopathological factors predictive of lymph node metastasis

From: Restoration of E-cadherin expression by selective Cox-2 inhibition and the clinical relevance of the epithelial-to-mesenchymal transition in head and neck squamous cell carcinoma

Variable

 

n

LN metastasis (-) n = 15

LN metastasis (+) n = 25

p value

Agea

< 60

25

9

(36.0%)

16

(64.0%)

0.724

 

≧ 60

15

6

(40.0%)

9

(60.0%)

 

Gendera

Male

35

15

(42.9%)

20

(57.1%)

0.081

 

Female

5

0

(0.0%)

5

(100.0%)

 

T classificationb

1

2

1

(50.0%)

1

(50.0%)

0.036*

 

2

10

7

(70.0%)

3

(30.0%)

 
 

3

22

4

(18.2%)

18

(81.8%)

 
 

4

6

3

(50.0%)

3

(50.0%)

 

Histological gradeb

I

21

7

(33.3%)

14

(66.7%)

0.551

 

II

12

6

(50.0%)

6

(50.0%)

 
 

III

7

2

(28.6%)

5

(71.4%)

 

Vascular invasiona

Negative

32

13

(40.6%)

19

(59.4%)

0.350

 

Positive

8

2

(25.0%)

6

(75.0%)

 

Lymphatic invasiona

Negative

22

11

(50.0%)

11

(50.0%)

0.069

 

Positive

18

4

(22.2%)

14

(77.8%)

 

Perineural invasiona

Negative

30

13

(43.3%)

17

(56.7%)

0.174

 

Positive

10

2

(20.0%)

8

(80.0%)

 
  1. aFisher’s exact test, bChi-square test.
  2. *Statistically significant.
  3. LN = lymph node.