Figure 2
From: In silico and Ex vivo approaches identify a role for toll-like receptor 4 in colorectal cancer
TLR4 Expression by Colon Tissue Type. A) Mean TLR4 expression for normal colon, adenoma, and CRC stratified by each of the 4 probes for TLR4. Mean TLR4 expression was higher in colonic neoplasia than normal tissue for all probes with the macro-dissected specimens from GSE20916. B) Fold change for TLR4 expression was calculated using RMA. Mean FC for the normal-to-CRC, normal-to-adenoma, and adenoma-to-cancer samples for each TLR4 probe are presented. The lowest grade of histology is the reference standard for comparison within each column. The highest TLR4 fold change (FC) is in adenoma-compared-to-normal among all tissues tested.