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Figure 2 | Journal of Experimental & Clinical Cancer Research

Figure 2

From: AZD8931, an equipotent, reversible inhibitor of signaling by epidermal growth factor receptor (EGFR), HER2, and HER3: preclinical activity in HER2 non-amplified inflammatory breast cancer models

Figure 2

AZD8931 inhibits EGFR pathway protein expression. A. SUM149 cells were treated with vehicle control or 1 μmol/L AZD8931 for 4, 24, and 48 hrs. B. SUM149 and FC-IBC-02 cells were treated with 0 (vehicle), 0.01, 0.1, or 1 μmol/L AZD8931 for 24 hrs. Expression of EGFR, p-Akt, Akt, and β-Actin was examined by immunoblot analysis.

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