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Figure 5 | Journal of Experimental & Clinical Cancer Research

Figure 5

From: AZD8931, an equipotent, reversible inhibitor of signaling by epidermal growth factor receptor (EGFR), HER2, and HER3: preclinical activity in HER2 non-amplified inflammatory breast cancer models

Figure 5

AZD8931 inhibits EGFR pathway protein expression in vivo . A. Immunohistochemical analysis of EGFR, HER2, HER3, phospho-EGFR, phospho-HER2, and phospho-HER3 in SUM149 xenografts following AZD8931 acute treatment (50 mg/kg/per day × 4 days). B. The average of pathologist’s H-score for both membrane and cytoplasmic staining.

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