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Table 2 IC:50s at 72 h of different UTR agonists and antagonists on bladder cancer cell lines

From: Urotensin II receptor determines prognosis of bladder cancer regulating cell motility/invasion

Cell lines Compounds IC:50 (nM)
  UII Urantide UPG83 UPG85 UPG84
T24 n.d. 350 ± 8 n.d. n.d. 7 ± 0,6
RT112 n.d. 375 ± 6 n.d. n.d. n.d.
MCR n.d. n.d n.d. n.d. 9,8 ± 0,5
HT1376 n.d. n.d. 1000 ± 9 n.d. 7,9 ± 0,4
  1. n.d.: not detectable; IC:50: drug concentration that induces the 50% of cell growth inhibition after 72 h from the beginning of the treatment; UII: urotensin II.