Figure 4

Statistical analysis of miR-223, miR-886-3p, and miR-34c-5p expression by in situ hybridisation (ISH). The expression percentage of miR-223, miR-886-3p, and miR-34c-5p was statistically analysed in extranodal NK/T-cell lymphoma, nasal type (EN-NK/T-NT), peripheral T-cell lymphoma and inflammatory nasal mucosa cases by ISH. Statistically, ISH results revealed that the expression level of miR-223 was significantly higher in EN-NK/T-NT cases than in peripheral T-cell lymphoma (A, ^※P = 0.013) and in inflammatory nasal mucosa (A, ^※※P = 0.043). Similarly, miR-886-3p expression upregulated in EN-NK/T-NT cases compared to peripheral T-cell lymphoma (B, ^#P = 0.028) and inflammatory nasal mucosa (B, ^##P = 0.022). However, the expression level of miR-34c-5p (C, ^∆P = 1.000 and ^∆∆P = 0.254) did not differ significantly between these 3 groups.