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Table 2 Correlation of PRDM1 and miR-223 expression with clinical factors and prognostic value

From: The downregulation of PRDM1/Blimp-1 is associated with aberrant expression of miR-223 in extranodal NK/T-cell lymphoma, nasal type

   

PRDM1 expression

   

miR-223 expression

 
 

n

Percent

Negative

Positive

P

n

Percent

Negative

Positive

P

Patients

61

    

31

    

male

34

55.74

26

8

0.829

19

61.29

5

14

0.704

female

27

44.26

20

7

 

12

38.71

4

8

 

Age (year)

61

    

31

    

<40

29

47.54

21

8

0.463

13

41.94

4

9

NA※

40-60

20

32.79

17

3

 

11

35.48

2

9

 

>60

12

19.67

8

4

 

7

22.58

2

5

 

Stage ∆

46

    

26

    

І/ІІ

18

39.13

9

9

0.009

9

34.62

3

6

0.661

III/IV

28

60.87

24

4

 

17

65.38

4

13

 

Outcome

35

    

21

    

alive

12

34.29

6

6

0.038

8

38.10

3

5

0.325

dead

23

65.71

20

3

 

13

61.90

2

11

 

5-year OS

35

    

21

    

Mean ± SD

  

39.49 ± 9.62

64.02 ± 11.48

0.045

  

53.40 ± 18.41

45.70 ± 10.05

0.504

OS

35

    

21

    

Mean ± SD

  

44.72 ± 10.41

64.02 ± 11.48

0.084

  

53.40 ± 18.41

52.84 ± 10.70

0.784

FFS

35

    

21

    

Mean ± SD

  

26.50 ± 5.60

57.41 ± 11.60

0.042

  

43.20 ± 16.89

38.99 ± 7.84

0.691

  1. ※NA, not analyzed, because of limited sample size.
  2. â–³Ann Arbor Stage.